CSIR-Central Drug Research Institute, Lucknow
Atul Goel obtained a Ph.D. in Bioorganic and Medicinal Sciences from the Central Drug Research Institute (CDRI), Lucknow (1998) and postdoctoral research at the National Institutes of Health (NIH), Bethesda, USA, during1999-2001. In November 2001, he joined the CSIR-CDRI as faculty, currently working as Chief Scientist. He has guided several doctoral and postdoctoral fellows and has more than 24 years of research experience. He has published >115 peer-reviewed research articles in journals of high repute and has ~20 national and international patents. His research interests include discovering and developing new affordable medicines/technologies in the area of Osteoporosis and bone disorders. He was elected fellow of the Indian Academy of Sciences in 2021.
Lectures by Fellows/Associates
G V Anand, Dayanand Sagar University, Bengaluru
Development of Donor-Acceptor Based Fluorescent Dyes for Diagnostics and Biomedical Applications
Over the last two pandemic years, we have pioneered breakthrough innovation of basic building blocks (novel universal quencher and fluorescent dyes) for synthesizing TAQMAN-like probes and alternate conjugation-chemistry to develop complete RT-PCR kits for the detection of SARS-CoV-2 and its variants. Our patented platform technology for a novel quencher ‘UniQ’ and fluorescent dyes was successfully demonstrated for developing two qRT-PCR Diagnostic Kits, INDICoV (SARS-CoV2) and INDICoV-Om (Omicron variant), and validated by the government agencies and institutions. Furthermore, our group is engaged in developing efficient approaches for synthesizing new organic fluorescent dyes with absorption and emission at various wavelengths for biomedical and diagnostics applications. Innovatively, we have designed and synthesized Donor-Acceptor based Fluoranthene (FLUN-550) and Azafluorene (AF-575) Dye for selective staining of cytoplasmic lipid droplets of 3T3-L1 pre-adipocytes as well as for selective staining of neutral lipid droplets of <i>Leishmania donovani</i> parasite and soil nematode <i>C. elegans</i> for live and fixed cell imaging applications. We have discovered the ‘First’ dual colorimetric-ratiometric fluorescent probe for selective and direct visualization of Labile Iron (III) pools in multicellular organisms (Soil nematode <i>C. elegans</i>).